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Tyrosine kinase inhibitors (TKIs) are the mainstay of treatment for patients with EGFR mutation–positive non–small cell lung cancer (NSCLC), according to the most recent guideline on management of NSCLC issued by the National Comprehensive Cancer Network (NCCN).

All women with ovarian cancer should have the option of genetic testing, regardless of tumor histology, investigators in a retrospective, tissue-based analysis of a randomized trial concluded.

A higher score on a composite index of homologous recombination deficiency (HRD) correlated with improved progression-free survival (PFS) and overall survival (OS) in ovarian cancer treated with platinum-containing chemotherapy, results of a tissue- based validation study showed.

Targeted therapies used to treat hematologic malignancies can cause unintended cardiac toxicity in some patients and can lead to cardiac-related mortality, according to study results presented at the American Association for Cancer Research Annual Meeting.

The authors describe the development of a web-based navigation application, study design, conduct of the study, and the results of the usability assessment of the navigation application by trial participants.

Through assessment, shared decision-making, and identifying and coordinating resources, patient navigators can make care more accessible and may increase adherence to screening and timely diagnostic follow-up care and cancer treatment.

The following are a selection of key clinical trials that are currently recruiting patients for inclusion in investigations of new therapies and new regimens of available therapies for patients with multiple myeloma. Each clinical trial description includes the NLM Identifier to be used as a reference with ClinicalTrials.gov. The information below can help oncology practice managers and providers direct their eligible patients to one of these clinical trials.

Within the multidisciplinary team, the navigator works as an advocate, care provider, educator, counselor, and facilitator to ensure that every patient receives comprehensive, timely, and quality healthcare services.

The authors present a case study highlighting the importance of patients’ physical and mental preparedness for the recommended medical treatments.