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The randomized phase 3 JCOG1205/1206 trial did not demonstrate superiority of irinotecan + cisplatin versus etoposide + cisplatin in patients with completely resected high-grade neuroendocrine carcinomas (HGNECs) of the lung.

The ongoing nonrandomized, open-label, single-arm phase 2 NICE-NEC trial is evaluating the safety and efficacy of adding the immune checkpoint inhibitor nivolumab to standard platinum-doublet chemotherapy as first-line therapy in patients with metastatic or unresectable grade 3 neuroendocrine neoplasms (NENs) of gastroenteroenpathic (GEP) or unknown origin.

Results of a retrospective analysis showed that checkpoint inhibitors as monotherapy had limited clinical benefit in patients with grade 3 neuroendocrine tumors (NETs) or neuroendocrine carcinomas (NECs), and modest benefit when combined with another checkpoint inhibitor or chemotherapy.

Combined data from two phase 2 trials indicate that avelumab monotherapy had limited antitumor activity in patients with grade 2/3 neuroendocrine neoplasms (NENs).

Attendees seeking to maximize the educational benefits of the conference took part in 4 preconference workshops, addressing topics including genetics and genomics, financial navigation amid the COVID-19 pandemic, professional development, and motivational interview skills for navigators.

Honoring the best in the navigation field, the AONN+ awards are presented each year in various professional categories, also recognizing a patient for outstanding contributions to the cancer community with the CONQUER: the patient voice Hero of Hope Award.

Allowing providers to connect with and care for their patients without in-person visits, telehealth has surged during the COVID-19 pandemic. While advocates push for the expansion of telehealth and the opportunities it represents, providers and patients seek to overcome associated challenges.

The culmination of a mission to create standardized metrics by which navigation programs can demonstrate outcomes and value, the AONN+ Navigation Metrics Toolkit provides guidance for putting the metrics into practice.

In a timely keynote presentation that struck home for navigators, Bina Parekh, PhD, discussed the profound impact of vicarious trauma and how to develop the resilience to transform it into something positive.

Amid the anguish of a cancer diagnosis, childbearing may be far from a patient’s mind. However, fertility preservation is an important consideration, which providers must be prepared to discuss.