Lung Cancer

Immune checkpoint inhibitors cause rare severe adverse events in patients, but most patients improve with treatment.
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Patients with NSCLC harboring KRAS G12C have distinct imaging patterns from patients with other NSCLC genetic mutations.
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Despite guideline recommendations, a retrospective study found inadequate biomarker testing rates to direct targeted therapy.
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Researchers highlighted promising research into early-stage diagnostics and therapies for NSCLC harboring the KRAS G12C mutation discussed in a review article.
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A recent study found that chronic pneumonitis is a rare complication of immune checkpoint inhibitor therapy in patients with NSCLC.
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A retrospective analysis demonstrated a 10-point difference in receipt of NGS testing between white and black patients with NSCLC.
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2021 Midyear Review: Non–Small-Cell Lung Cancer

Recently released study results report similar chemo-immunotherapy outcomes in KRAS-mutant NSCLC subtypes and poor results in patients with concurrent STK11 and/or KEAP1 mutations.
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A recently released retrospective study demonstrates that NSAID use in patients with NSCLC enhances immune checkpoint efficacy.
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Subgroup analysis of CodeBreaK 100 trial results found that sotorasib achieved a response in pretreated patients with KRASG12C-mutated NSCLC subtypes.
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Page 12 of 24

Journal of Oncology Navigation & Survivorship
JONS

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