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Pembrolizumab as second-line therapy improved overall survival (OS) in patients with advanced or metastatic esophageal cancer and high PD-L1 expression compared with chemotherapy, according to findings from the phase 3 KEYNOTE-181 study presented at the 2019 Gastrointestinal Cancers Symposium.

Adjuvant treatment with durvalumab, a checkpoint inhibitor, in patients with residual disease after trimodal therapy for advanced esophageal or gastroesophageal junction (GEJ) adenocarcinoma was associated with a 79% 1-year relapse-free survival rate in a phase 2 clinical trial.

The era of immunotherapy has opened new perspectives in renal cell carcinoma (RCC), which is one of the tumors most highly infiltrated with cluster of differentiation T cells and PD-1 expression, partially accounting for its sensitivity to immunotherapy.

First-line therapy with pembrolizumab plus axitinib significantly improved overall survival (OS), progression-free survival (PFS), and objective response rates compared with standard-of-care sunitinib in patients with clear cell metastatic renal cell carcinoma (RCC) in KEYNOTE-426.

The combination of the PD-1 inhibitor durvalumab and the CTLA-4 inhibitor tremelimumab added to best supportive care improved overall survival (OS) by >2 months compared with best supportive care alone in a phase 2 randomized trial of unselected patients with refractory colorectal cancer (CRC).

Ensure the success and sustainability of your navigation program with metrics.

The word “acuity” is used frequently in healthcare literature; however, the true concept of acuity is sometimes misunderstood.

Experts discuss the highly anticipated CAPE Lung Cancer web-based library.

The authors present their study of an adapted model of patient navigation and its impact in addressing cancer treatment and management challenges across the Caribbean region.

The authors present results from a scoping review as evidence that will aid in the development of an oncology patient navigation–specific acuity tool.