This video interview series features Neal Shore, MD, and Stephen Rowe, MD, PhD, who share their expert insights and perspectives on innovation in the imaging of patients with prostate cancer and the identification of metastases. Topics covered include recent advances in PSMA-directed imaging, the advantages of PET imaging, and the fusion of PET/CT or PET/MRI techniques. In addition, they also discuss the OSPREY and CONDOR clinical studies that led to the approval of PYLARIFY® (piflufolastat F 18) by the FDA in May 2021.