Genetics & Genomics

Over the past 5 years, there have been 20 FDA approvals of novel genetic medicine technologies – and this is just the beginning. Here’s a glimpse of what’s coming ahead.
In this roundtable discussion presented by AONN+ and supported by Exact Sciences, a panel of experts discuss the critical role of nurse navigators in educating cancer patients about genomic testing and how to interpret the results.
Navigators can meet the ever-growing needs of patients undergoing genetic testing. Here’s how.
KRAS-mutant tumors are notoriously difficult to treat. Early data presented at the 2020 virtual meeting of the American Association for Cancer Research suggest 2 new routes to treating KRAS-mutated cancers: (1) the combination of a RAF/MEK inhibitor and a FAK inhibitor, and (2) onvansertib, a competitive inhibitor of the PLK1 enzyme, together with chemotherapy.
Understanding the functions of different tissues in the body is key to understanding genetics and genomics.
Germline testing should now be considered for any patient with pancreatic cancer, and molecular analysis of tumors should be considered in patients with metastatic disease, according to the most recent National Comprehensive Cancer Network (NCCN) guideline (version 1.2019) for the management of pancreatic cancer.
Precision medicine is now a mainstay in cancer care, bringing to light the importance of genomic literacy among providers, according to Kate Reed, MPH, ScM, from The Jackson Laboratory in Bar Harbor, ME.
Jennifer R. Klemp, PhD, MPH presented “Genetics and Genomics: How Does Navigation Fit In?” at the Sixth Annual Academy of Oncology Nurse & Patient Navigators (AONN+) Conference in Atlanta, GA. “The real role of genomic medicine and where we’re going is that we do want to be more personalized,” Dr Klemp said. “The larger panel in genomic testing is going to keep taking us in that direction.”

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