2021 Year in Review - Gastrointestinal Cancer
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
Clinical study results indicate pembrolizumab monotherapy improves response rate in patients with advanced refractory esophageal cancer.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
Avelumab maintenance therapy conveys no overall survival difference over the use of continued chemotherapy in patients with advanced GEJC or gastric cancer.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
The dose-escalation phase of the EMERGE clinical trial results show that 200 mg domatinostat twice daily is safe and efficacious.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
No survival advantage was observed with durvalumab use in the PLATFORM clinical trial, but a patient subgroup was observed to have a radiological response.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
CheckMate-577 clinical trial results show nivolumab adjuvant therapy increases disease-free survival over placebo in patients with gastroesophageal junction (GEJ) cancer or esophageal cancer.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
Second-line or later nivolumab monotherapy yields no clear evidence of efficacy advantage for patients with advanced esophageal cancer.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
Recently released positive findings from the LEAP-005 trial of lenvatinib plus pembrolizumab in the treatment of previously treated gastric cancer leads to cohort expansion.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
Results from the CheckMate-648 study demonstrate that nivolumab added to either ipilimumab or chemotherapy improves overall survival in patients with advanced esophageal squamous-cell carcinoma.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
DKN-01 plus tislelizumab and CAPOX combination demonstrates promising response rates and safety data in phase 2a study.
2021 Year in Review - Gastrointestinal Cancer | December 1, 2021
Nivolumab combined with chemotherapy had improved survival outcomes and an acceptable safety profile in patients with advanced gastric/esophageal cancer, according to CheckMate-649 study results.