Sara A. Hurvitz, MD
University of California, Los Angeles/Jonsson Comprehensive Cancer Center, Los Angeles, CAAuthored Items
Sami Diab, MD, Hope S. Rugo, MD, Lida A. Mina, MD, Shannon Puhalla, MD, Reshma Mahtani, DO, N. Lynn Henry, MD, PhD, Neelima Denduluri, MD, Denise Yardley, MD, Yao Wang, MD, Lillian Shahied Arruda, PhD, Iulia C. Tudor, PhD, Eric Gauthier, PharmD, PhD, Akos Czibere, MD, PhD, Jennifer K. Litton, MD, Sara A. Hurvitz, MD
November 2019 Vol 10, No 11
Talazoparib is a poly(ADP-ribose) polymerase (PARP) inhibitor approved in the US for HER2-negative germline BRCA1/2-mutated (gBRCA1/2mut) locally advanced/metastatic breast cancer.
November 2018 Vol 9, NO 11
Endocrine therapy (ET) is an established treatment for premenopausal women with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–negative (HER2−) advanced breast cancer (ABC). MONALEESA-7 (NCT02278120) was the first phase 3 randomized trial of a cyclin-dependent kinases 4 and 6 inhibitor (ribociclib) + ET in premenopausal women with HR+/HER2− ABC without prior ET for ABC.
Last modified: November 6, 2019