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November 2017 VOL 8, NO 11


Letters from Lillie

AONN+ to Present Evidence-Based Navigation Research Abstracts at Annual Conference

Lillie D. Shockney, RN, BS, MAS, ONN-CG, The Johns Hopkins Breast Center; the Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD

 

Dear Navigators, In this issue of the Journal of Oncology Navigation & Survivorship (JONS), we are proud to present the evidence-based research abstracts that have been accepted to the Eighth [ Read More ]

Category I: Community Outreach/Prevention, Eighth Annual AONN+ Conference Abstracts

Community Outreach: Inside a Community Tumor Board. Prevention, Treatment, and Survivorship in Breast Cancer

Melanie Lynch, MD, FACS; Sharon Lieb Inzetta, RN, MS, CBCN, CN-BN; Heidi Eve-Cahoon, MSN, RN, CNP, CBCN; Laura Musarra, BS, MBA
Summa Health, Akron, OH 

Background: Today there are ever-increasing challenges surrounding breast cancer care. The ongoing disparities in delivering cancer care continue to impact our nation as a whole, and, more importantly, for both [ Read More ]

Category I: Community Outreach/Prevention, Eighth Annual AONN+ Conference Abstracts

Early Outcomes of a Pancreatic Cancer Familial Risk Assessment Program

Stacey L. Webb, MPA-HCA, BSN, RN, ONN-CG; Nora J. Barrett, BSN, RN, OCN, ONN-CG; Kristi C. Garrison, MS, CHES, CHW, OPN-CG; Kristi M. Griffith, MSN, RN, CHPN
Baylor Charles A. Sammons Cancer Center at Dallas, Dallas, TX 

Background: Currently, pancreatic cancer (PC) is the fourth leading cause of cancer mortality in the United States. However, with the lack of early detection tests and treatment options, it is [ Read More ]

Category I: Community Outreach/Prevention, Eighth Annual AONN+ Conference Abstracts

Lung Cancer Screenings – Winning Battles in the Lung Cancer War

Amy M. Norton, RN, MSN, ONN-CG (T); Dawn M. Deacon, RN, BSN, OCN, ONN-CG; Wendy L. Brooks, RN, ONN-CG (T)
Sarah Cannon Cancer Institute – HCA Midwest Health, Kansas City, MO 

Background: According to Morgan,1 “Lung Cancer is the leading cause of cancer-related death in the United States, claiming more lives than colon, breast, and prostate cancer combined.” A projected “222,500 [ Read More ]

Category I: Community Outreach/Prevention, Eighth Annual AONN+ Conference Abstracts

Real-Time Breast Cancer Risk Assessment at Screening Mammography

Kathy Albano, RN, BSN, CN-BN
Beekley Center for Breast Health & Wellness
Bristol Hospital, Bristol, CT
 

Background: Each woman’s risk of developing breast cancer is different and depends on her lifestyle, family health history, and other factors. The American Cancer Society considers women who have a [ Read More ]

Category II: Care Coordination/ Care Transitions, Eighth Annual AONN+ Conference Abstracts

Benefits of Implementing an Automated Workflow Cancer Conference Platform

Lijo Simpson, MD; Anju Mathew, MBA; Doris Jones, MSN, RN, OCN; Kim Gullion, MSN, RN, OCN;
George Miranda
DeKalb Medical, Atlanta, GA 

Background: The tumor board, or multidisciplinary cancer conference (MCC), is the foundation of high-value multidisciplinary oncology care through coordinating teams of specialists. Benefits of MCCs include coordination, direction for complicated [ Read More ]

Category II: Care Coordination/ Care Transitions, Eighth Annual AONN+ Conference Abstracts

Creating a Pediatric Cancer Immunotherapy Nurse Navigator Role: Developing Complex Care Coordination Processes

Claire White, BSN, RN, CPHON
The Children’s Hospital of Philadelphia,
Philadelphia, PA
 

Background: Accessing chimeric antigen receptor (CAR) T-cell clinical trials for relapsed and refractory B-cell acute lymphoblastic leukemia (ALL) is challenging for pediatric patients who have experienced a relapse of B-cell [ Read More ]

Category II: Care Coordination/ Care Transitions, Eighth Annual AONN+ Conference Abstracts

Improving Compliance and Patient Outcomes with a Presurgery Gynecologic Oncology Educational Video and Survey

Antoinette Solnik, RN, BSN, ONN-CG, RYT-200; Allison Steinberg, MSN, MPH, RN, OCN
The Johns Hopkins Department of Obstetrics & Gynecology, Division of Gynecologic Oncology, Sibley Memorial Hospital
Washington, DC
 

Background: The Johns Hopkins Department of Obstetrics & Gynecology, Division of Gynecologic Oncology, Sibley Memorial Hospital, performs more than 500 surgeries annually. After creating an initial written postoperative educational tool, [ Read More ]

Category II: Care Coordination/ Care Transitions, Eighth Annual AONN+ Conference Abstracts

The Oncology Nurse Navigator’s Role in Enhancing the Multidisciplinary Cancer Conference at a Community Cancer Hospital

Heather Hannon, MSN, RN, CBCN, OCN, ANP-BC
Sarah Cannon Cancer Institute at Johnston Willis Hospital
Richmond, VA
 

Background: The multidisciplinary cancer conference (MCC) plays an integral role in optimizing patient outcomes in today’s increasingly complex world of cancer care. MCCs offer multiple benefits, including increased use of [ Read More ]

Category III: Patient Advocacy/ Patient Empowerment, Eighth Annual AONN+ Conference Abstracts

A Patient/Provider Discussion Tool for Chronic Myeloid Leukemia

Claire Saxton, MBA1; Heather Hollen, MS1; Jenny Karubian, MA2; Alexandra Zaleta, PhD2
1Cancer Support Community, Washington, DC
2Cancer Support Community, Research and Training Institute
Philadelphia, PA
 

Background: The Cancer Support Community (CSC) has designed a patient/provider discussion tool for patients with chronic myeloid leukemia (CML). The main goal of the tool is to help patients and [ Read More ]

Category III: Patient Advocacy/ Patient Empowerment, Eighth Annual AONN+ Conference Abstracts

Carcinoid Syndrome Impact Survey: Evaluation of the Burden of Illness and the Gap Between Patient and Oncologist Perceptions

Grace Goldstein, MA1; Kathleen Evans, MBA2; Arpan Shah, PharmD, MBA3; Pablo Lapuerta, MD3
1Carcinoid Cancer Foundation, White Plains, NY;
2Healogix, LLC, Horsham, PA;
3Lexicon Pharmaceuticals, Inc,
The Woodlands, TX
 

Background: Patients with advanced neuroendocrine tumors may develop carcinoid syndrome, a rare condition characterized by debilitating symptoms, including diarrhea, flushing, and valvular heart damage, that can greatly affect patient social [ Read More ]

Category III: Patient Advocacy/ Patient Empowerment, Eighth Annual AONN+ Conference Abstracts

Structured Exercise Prescription Program: Targeting Monolingual Spanish-Speaking Patients to Improve Impairments

Lisa Ross, BS, ACSM/ACS Certified Cancer Exercise Trainer; Tracy Mazour, RN, MSN, OCN; Stephanie Mamantov, ACSM/ACS Certified Exercise Trainer; Emily Berry, MSPH; Aurelio Rodriguez; Keith Argenbright, MD
Moncrief Cancer Institute/UT Southwestern,
Fort Worth, TX
 

Background: Exercise is a multipurpose tool that can be used to help cancer survivors improve their quality of life (QOL) across the cancer continuum. Cancer and its treatments result in [ Read More ]

Category IV: Psychosocial Support, Assessment, Eighth Annual AONN+ Conference Abstracts

A Quantitative and Qualitative Quality-of-Life Evaluation of a Large Navigation Team

Background: Sarah Cannon Cancer Institute, the Oncology Service line for Medical City Healthcare in the Dallas/Fort Worth, Texas area, has a team of 13 disease-suite oncology nurse navigators and 2 [ Read More ]

Category IV: Psychosocial Support, Assessment, Eighth Annual AONN+ Conference Abstracts

Efficacy of the Breast Cancer Navigator Role in Reducing Distress in Newly Diagnosed Breast Cancer Patients: A Pilot Study

Patricia Johnson, BS, RN, OCN, CBCN1; Anne Bongiorno, PhD, APHN-BC, CNE2
1University of Vermont Health Network – CVPH;
2State University of New York at Plattsburgh
 

Background: Each year at a rural northeastern hospital, approximately 100 women and men are diagnosed with breast cancer. For most patients, this is a first diagnosis with cancer. Patients receive [ Read More ]

Category IV: Psychosocial Support, Assessment, Eighth Annual AONN+ Conference Abstracts

Examining the Mutual Benefits of a Peer Support Program to Facilitate Adaptation Among Women Affected by Breast/Ovarian Cancer: The Sharsheret Experience

Adina Fleischmann, LSW; Elana Silber, MBA; Melissa Rosen, MA
Sharsheret, Teaneck, NJ  

Background: Frank Riessman’s Helper Theory (1965) posits that peer support networks can be powerful tools to extend care delivery—benefiting both the giver and receiver of informal care. Studies continue to [ Read More ]

Category IV: Psychosocial Support, Assessment, Eighth Annual AONN+ Conference Abstracts

Quality of Life of Caregivers to Those Living with Chronic Myelogenous Leukemia

Ian Kudel, PhD1; Susan Gabriel, MS2; Erika Szabo, MPH, MSPharm2; Jifang Zhou, MD, MPH3; Ashutosh K. Pathak, MD, PhD, MBA, FRCP(Edin)2; Boxiong Tang, MD, PhD2; Nicola Brooksbank, BSN, RN, OCN4; Ryan Liebert, MS1
1Kantar Health, New York, NY;
2Teva Pharmaceuticals, Frazer, PA;
3University of Illinois at Chicago, College of Pharmacy, Chicago, IL;
4Duke University Hospital, Durham, NC
 

Background: Research has consistently found that caregivers for people with cancer report distress; however, it is not clear whether recent improvements in the treatment of chronic myelogenous leukemia (CML) have [ Read More ]

Category IV: Psychosocial Support, Assessment, Eighth Annual AONN+ Conference Abstracts

Screening for Supportive Oncology Patient Concerns, Analyzing Impact and Opportunities to Improve Spiritual Questions Affecting Navigation to Spiritual Resources

Stephanie Merce Boecher, RN, OCN, MSN, BSN, BA1; Julia R. Trosman, PhD, MBA2; Carol Newsom, RN3; Rosa Berardi4; Javier Macias, BA5; Dirk Labuschagne, MDiv6; Harry Miranda-Ocasio, PsyD6; James Gerhart, PhD7; Teresa Lillis, PhD7; Pam Khosla, MD8; Catherine Cassingham, MSW, LSW8; Anne Bowman, MBA, CHES9; Ana Gordon, AM, LCSW10
1Advocate Health Care;
2The Center for Business Models in Healthcare;
3Mercy Hospital and Medical Center;
4The Coleman Foundation;
5The Leukemia & Lymphoma Society;
6John H. Stroger Jr. Hospital of Cook County;
7Rush University Medical Center;
8Mount Sinai Hospital;
9UnityPoint Health – Peoria;
10University of Illinois Hospital & Health Sciences
 

Background: The Institute of Medicine (IOM) 2013 report recommends that supportive oncology care start at cancer diagnosis; the Commission on Cancer (CoC) Standard 3.2 requires distress screening and indicated action. [ Read More ]

Category IV: Psychosocial Support, Assessment, Eighth Annual AONN+ Conference Abstracts

The Emotional Journey Among Caregivers of Patients with Leukemia: The Caregivers’ Perspective Based on Social Media Listening

Susan Gabriel, MS1; Kerri Phillips, MBA2; Erika Szabo, MPH, MSPharm1; Mary Ann Slater, MBA3; Jifang Zhou, MD, MPH4; Ashutosh K. Pathak, MD, PhD, MBA, FRCP(Edin)1; Nicola Brooksbank, BSN, RN, OCN5; Boxiong Tang, MD, PhD1; Lulu K. Lee, PhD6
1Teva Pharmaceuticals, Frazer, PA;
2Kantar Health, New York, NY;
3Kantar Health, London, UK;
4University of Illinois at Chicago, College of Pharmacy, Chicago, IL;
5Duke University Hospital, Durham, NC;
6Kantar Health, San Mateo, CA
 

Background: The burden of cancer has largely focused on the patient. However, caregivers also experience considerable burden. Objectives: This study’s aim was to use social media posts to better understand [ Read More ]

Category IV: Psychosocial Support, Assessment, Eighth Annual AONN+ Conference Abstracts

The Therapy Dog Will See You Now

Margaret Rummel, BSN, MHA, OCN, NE-BC; Laura Galindez, MSW, LSW; Heather Sheaffer, DSW, LCSW
Abramson Cancer Center,
Philadelphia, PA
 

Background: Animal Assisted Therapy (AAT) is a supportive therapy that is currently underutilized in the outpatient oncology setting. AAT has been used to provide support for cancer patients, but a [ Read More ]

Category V: Professional Roles and Responsibilities, Eighth Annual AONN+ Conference Abstracts

Educational Needs Related to Nursing Skill Level and Awareness of Navigating the Complexities of the Cancer Care Continuum

Sharon Gentry, RN, MSN, CBCN, AOCN, ONN-CG1; Lillie Shockney, RN, BS, MAS, ONN-CG2; Margaret V. Clark, MSc, RN, RRT-NPS, CMPP3
1Breast Nurse Navigator, Novant Health Derrick L. Davis Cancer Center, Winston-Salem, NC;
2Professor of Surgery, Professor of Breast Cancer, Johns Hopkins Hospital School of Medicine, Baltimore, MD;
3Clark Medical Writing, North Chesterfield, VA
 

Background: The Academy of Oncology Nurse & Patient Navigators conducted a 1.5-day live conference April 27-29, 2017, in Phoenix, AZ. Objectives: To provide education, promote discussion, and identify strategies to [ Read More ]

Category V: Professional Roles and Responsibilities, Eighth Annual AONN+ Conference Abstracts

Integrating Metrics and Role Delineation into a Navigation Program for Quality Improvement

Sandra Miller, MHSM, RN, NE-BC1; Carolyn Allsen, BSN, RN, OCN, ONN-CG2; Sylvia Brown, MS, RN, OCN, CNL, ONN-CG3; Krystie Fenton, BSN, RN, OCN4; Carol Kirton, BSN, RN, OCN5; Angela Sisk, MSN, RN, OCN, AHN-BC6; Deidra Teoh, MSN, RN, OCN, ONN-CG7
1Oncology Service Line; 2Memorial Hermann – The Woodlands; 3Memorial Hermann – The Medical Center; 4Memorial Hermann – Southeast & Pearland; 5Memorial Hermann – Northeast; 6Memorial Hermann – Greater Heights; 7Memorial Hermann – Southwest & Sugar Land 

Background: Since the inception of the oncology nurse navigator (ONN) program at Memorial Hermann Hospital System (MHHS) in 2009, the role of the ONN was vastly misunderstood, and the overall [ Read More ]

Category V: Professional Roles and Responsibilities, Eighth Annual AONN+ Conference Abstracts

Navigating the Course from Diagnosis to Survivorship: The Implementation of the Nurse Navigator Role in a Pediatric Oncology Cancer Center

Peggy Townsend, MSN, RN, CPON; Jackie Gonzalez, DNP, MBA, ARNP, NEA-BC, FAAN; Lilliam Rimblas, RN, BSN, CPHON
Nicklaus Children’s Hospital, Miami, FL 

Background: Navigation is defined as the “guiding force promoting the timely movement of the patient through a complex system of care.” Evidence from leading adult cancer centers has shown that [ Read More ]

Category VI: Research, Quality, Performance Improvement, Eighth Annual AONN+ Conference Abstracts

Benefits of a Multidisciplinary Clinic Operations Workgroup as a Forum for Navigator Coordinators and Quality Improvement

Alyssa Pauls, RN, BSN, OCN; Cynthia Smith, RN, BSN, MA, OCN; Kathleen Sevedge, RN, MA, AOCN; Laura Beaupre, RN, BSN, OCN, CN-BN; Maritza Chicas, RN, BSN, OCN; Jeanne Kenna, RN, OCN; Angela Miller, RN, MEd, OCN; Raizalie Roman, RN, BSN, OCN; Jane Zubia, RN, OCN, CN-BN
Lehigh Valley Health Network Cancer Institute, Allentown, PA  

Background: Multidisciplinary care is recognized as a sign of quality cancer care according to several organizations, including the American Society of Clinical Oncology, the Institute of Medicine, the National Cancer [ Read More ]

Category VI: Research, Quality, Performance Improvement, Eighth Annual AONN+ Conference Abstracts

Effectiveness of the Managing Cancer at Work Program

Marie Borsellino, RN, MSN, ONN-CG
Johns Hopkins, Baltimore, MD 

Background: The number of cancer survivors is increasing because of advances in detection and treatment. More than 15.5 million Americans with a history of cancer were alive as of January [ Read More ]

Category VI: Research, Quality, Performance Improvement, Eighth Annual AONN+ Conference Abstracts

Helping Breast Cancer Patients Manage Care Transitions Through Patient and Navigator Use of 4R Care Plans, 4R = Right Information/Care/Patient/Time

Julia R. Trosman, PhD, MBA1,2; Jennifer Stein, RN3; Valerie Nelson, MD, MBA4; Jennifer Tepper, MSN, APN, CBCN, CNS4; Cathy Spagnoli, MSHA, RN, CBCN, CN-BN, ONN-CG5; William J. Gradishar, MD, FASCO, FACP6; Claudia B. Perez, DO7; Mikele Bunce, MPH, PhD8; Wayne Pan, MD, PhD8; Liliana Mendoza, RN7; Alma Sotelo, CN-BA7; Swati Kulkarni, MD1; Lynn Galuska Elsen, RN, BSN, IBCLC3; Christine Weldon, MBA2
1Northwestern University; 2The Center for Business Models in Healthcare; 3Northwestern Medicine; 4Northwestern Medicine Lake Forest; 5Northwestern Lake Forest Hospital; 6Mercy Hospital and Medical Center; 7Genentech 

Background: Transitions in care require well-managed timing and sequencing of events across specialties. The IOM 2011 and 2013 reports recommend a written care plan at cancer diagnosis to enable cross-discipline [ Read More ]

Category VI: Research, Quality, Performance Improvement, Eighth Annual AONN+ Conference Abstracts

Impact of a Workplace Educational Webinar Series Focused on the Needs of Employees and Their Family Members Living with a Cancer Diagnosis

Marie Borsellino, RN, MSN, ONN-CG
Johns Hopkins, Baltimore, MD 

Background: As people with a history of cancer are living longer and surviving their cancer, today it is estimated that there are 14 million cancer survivors in the United States. [ Read More ]

Category VI: Research, Quality, Performance Improvement, Eighth Annual AONN+ Conference Abstracts

Impact on Caregivers of Patients (Pts) with Myeloproliferative Neoplasms (MPNs) in the United States: Results from the Living with MPNs (LWMPN) Survey

Dilan Paranagama, PhD1; Shreekant Parasuraman, BPharm, PhD1; Andrew Bai, MS1; Jingbo Yu, PhD1; Ruben Mesa, MD, FACP2
1Incyte Corporation, Wilmington, DE; 2Mayo Clinic, Scottsdale, AZ 

Background: The MPNs myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET) are associated with a variety of burdensome symptoms (BMC Cancer. 2016;16:167) and reduced survival compared with the general [ Read More ]

Category VI: Research, Quality, Performance Improvement, Eighth Annual AONN+ Conference Abstracts

Virtual Oncology Navigation Program: Patient Hotline Access for Self-Advocacy

Joyce Schaffer, RN, MSN, AOCNS; Susan G. Haag, PhD, MS; Janet Eriksen, BSN, BA, RN; Mary Jo Baldwin, AA; Erkut Borazanci, MD; Dan Von Hoff, MD
HonorHealth Research Institute, Scottsdale, AZ 

Background: Patient navigation has been shown to improve patient engagement and participation in clinical trials1-3 and reduce barriers to cancer care.4,5 Despite growing evidence of value, oncology patient navigation is [ Read More ]

Category VII: Operations Management, Organizational Development, Health Economics, Eighth Annual AONN+ Conference Abstracts

Can Transparency of Individual Navigation Performance Improve Overall Navigation Program’s Operational and Quality Metrics?

Jill Dodson, LSW, LMHC, LMFT, CCM; Charlotte Howard, MSN, RN, CBCN; Diane Von Ah, PhD, RN, FAAN; Adele Nielsen, BSN, RN; Sarah Dutkevitch, RN, OCN; Susan Storey, PhD, RN, AOCNS
Indiana University Health North Hospital, Carmel, IN 

Background: Sarah Cannon’s San Antonio market was seeking a way to effectively improve key quality and operational navigation metrics on their monthly Navigation Market Scorecard. The market scorecard was reflective [ Read More ]

Category VIII: Survivorship and End of Life, Eighth Annual AONN+ Conference Abstracts

If We Build It Will They Come?

Sandra Miller, MHSM, RN, NE-BC1; Carolyn Allsen, BSN, RN, OCN, ONN-CG2; Sylvia Brown, MS, RN, OCN, CNL, ONN-CG3; Krystie Fenton, BSN, RN, OCN4; Carol Kirton, BSN, RN, OCN5; Angela Sisk, MSN, RN, OCN, AHN-BC6; Deidra Teoh, MSN, RN, OCN, ONN-CG7
1Oncology Service Line; 2Memorial Hermann – The Woodlands; 3Memorial Hermann – The Medical Center; 4Memorial Hermann – Southeast & Pearland; 5Memorial Hermann – Northeast; 6Memorial Hermann – Greater Heights; 7Memorial Hermann – Southwest & Sugar Land 

Background: The American Cancer Society acknowledged an estimated 1,688,780 new cancer diagnoses by the end of 2017. A survivor is defined as, “any person with a history of cancer, from [ Read More ]

Category VIII: Survivorship and End of Life, Eighth Annual AONN+ Conference Abstracts

Impact of Perceived Cognitive Impairment on Work-Related Outcomes in Breast Cancer Survivors

Jill Dodson, LSW, LMHC, LMFT, CCM; Charlotte Howard, MSN, RN, CBCN; Diane Von Ah, PhD, RN, FAAN; Adele Nielsen, BSN, RN; Sarah Dutkevitch, RN, OCN; Susan Storey, PhD, RN, AOCNS
Indiana University Health North Hospital, Carmel, IN 

Significance: Work is central for most adults in the United States, including women with breast cancer. More than 90% of breast cancer survivors (BCS) in the United States return to [ Read More ]

Category VIII: Survivorship and End of Life, Eighth Annual AONN+ Conference Abstracts

The Healthy Forks Survivorship Series…Fighting Cancer One Fork at a Time

Jennifer Fitzgibbon, MS, RDN, CSO, CDN 

Background: Cancer patients must juggle doctor appointments; combat treatment side effects, while trying to maintain a sense of normalcy; and handle financial struggles. Stony Brook is a state-funded healthcare institution; [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Adverse Event Management During Treatment with Everolimus plus Exemestane for Postmenopausal Hormone Receptor–Positive (HR+), Human Epidermal Growth Factor Receptor 2–Negative (HER2–) Advanced Breast Cancer (ABC)

Jan Hronek; Lindsay Shelby
Sarah Cannon Research Institute, Nashville, TN 

Background: The combination of the mammalian target of rapamycin (mTOR) inhibitor, everolimus, and the aromatase inhibitor, exemestane, is approved for use in postmenopausal women with HR+, HER2– ABC after failure [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Biomarker Testing in Metastatic Non–Small Cell Lung Cancer: Process Gaps and Best Practices Reported by Nurse Navigators and Nurse Practitioners

Marc Chioda, PharmD1; Ahsan Jamil, PharmD1; Sukriti Kaushal, BS2; Joanne C. Ryan, PhD, RN1
1Pfizer, Inc; 2Atrium Staffing 

Objectives: This study describes the nurse perspective on the importance of biomarker testing for patients with metastatic non–small cell lung cancer (NSCLC) and identifies best practices and process gaps. Background: [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Biomarker Testing in Metastatic Non–Small Cell Lung Cancer: Process Gaps and Best Practices Reported by Nurse Navigators and Nurse Practitioners

Marc Chioda, PharmD1; Ahsan Jamil, PharmD1; Sukriti Kaushal, BS2; Joanne C. Ryan, PhD, RN1
1Pfizer, Inc; 2Atrium Staffing 

Objectives: This study describes the nurse perspective on the importance of biomarker testing for patients with metastatic non–small cell lung cancer (NSCLC) and identifies best practices and process gaps. Background: [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Efficacy and Safety of Ribociclib for the Treatment of Advanced Breast Cancer: A Review of Subgroup Analyses from the Phase 3 Trial MONALEESA-2

Andrea Watson, RN, BSN, OCN
Saint Luke’s Koontz Center for Advanced Breast Cancer, Kansas City, MO 

Background: Endocrine therapy is recommended for patients with hormone receptor–positive (HR+) advanced and metastatic breast cancer without visceral crisis (symptomatic visceral disease). Ribociclib is an orally bioavailable inhibitor of cyclin-dependent [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Evidence-Based Statistics on Complete Prevention and Rapid Sustained Elimination of Chemoradiation Mucositis by ProThelial—97% Reduction in Mucositis

Ricky W. McCullough, MD, MSc
MMI Translational Medicine Clinic and Research Center, Storrs, CT 

Background: Of the 1.6 million individuals annually diagnosed with cancer, 522,166 received chemoradation, with 234,975 developing toxic mucositis and 20% dying within 5 years due largely to mucositis-mediated unplanned treatment [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Frequency of Mutations in Multigene Panel Testing of 324 Ovarian and/or Endometrial Cancer Patients

Lilian Servais, MS, LCGC; Anjali Zimmer, PhD; Jeroen van den Akker, PhD; Will McFadden, PhD;
Alicia Y. Zhou, PhD
Color Genomics, Burlingame, CA 

Background: Endometrial and ovarian cancers are the sixth and seventh most common cancers in women worldwide.1 Inherited germline mutations in genes such as BRCA1 and BRCA2 have been identified in [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Patient-Reported Symptoms Reduce Health-Related Quality of Life Among Patients Undergoing Treatment for Metastatic Cancer

Dana Drzayich Antol, MS1; Adrianne W. Casebeer, PhD, MPP, MS1; Sari Hopson, PhD, MSPH1; Raya Khoury, MPH2; Aparna Parikh, MD2; Alisha Stein, RN-BC, MSN, OCN2; Todd Michael, PharmD, RPh2; Stephen Stemkowski, PhD, MHA1; Mikele Bunce, PhD, MPH2
1Comprehensive Health Insights, Humana, Louisville, KY; 2Genentech, San Francisco, CA 

Background: Symptoms that patients with cancer experience, either due to their illness or as a result of cancer treatment, are known to diminish their health-related quality of life. Objectives: This [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Pooled Analysis of Safety with Extended 3-Year Follow-up Across Combination Dabrafenib and Trametinib (D+T) Phase 3 Trials

Jean-Jacques Grob, MD, PhD1; Keith T. Flaherty, MD2; Georgina V. Long, MD, PhD3; Paul Nathan, MD4; Dirk Schadendorf, MD, PhD5; Antoni Ribas, MD, PhD6; Caroline Robert, MD7; Stephen Lane, MS8; Carmen Mak, PhD8; Bijoyesh Mookerjee, MD8; Michael A. Davies, MD, PhD9
1Aix-Marseille University, Marseille, France; 2Dana-Farber Cancer Institute/Harvard Medical School and Massachusetts General Hospital, Boston, MA; 3Melanoma Institute of Australia and The University of Sydney, Sydney, NSW, Australia; 4Mount Vernon Cancer Centre, Northwood, UK; 5University Hospital of Essen, Essen, Germany; 6UCLA and the Jonsson Comprehensive Cancer Center, Los Angeles, CA; 7Gustave Roussy Comprehensive Cancer Center, Villejuif, Paris-Sud, France; 8Novartis Pharmaceuticals Corporation, East Hanover, NJ; 9The University of Texas MD Anderson Cancer Center, Houston, TX 

Background: Significantly improved outcomes with D+T vs BRAF inhibitor (BRAFi) monotherapy have been demonstrated in phase 3 BRAF V600E/K–mutant mel­anoma trials (COMBI-d [NCT01584648]; COMBI-v [NCT01597908]), supporting use of D+T as [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Single-Agent Ibrutinib in Patients with Treatment-Naive and Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia: The 5-Year Experience

Fan Ny, NP; Jillian Settlemire, RN; Ying Luan, PhD; Alvina D. Chu, MD; Tony Lin; Steven E. Coutre, MD; John C. Byrd, MD
The Ohio State University Comprehensive Cancer Center, Columbus, OH 

Background: Ibrutinib, a B-cell receptor pathway inhibitor, is approved in the United States for the treatment of patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and allows for treatment without [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

The Chimeric Antigen Receptor T-Cell Treatment Journey: Patient and Nursing Education for Managing the ZUMA-1 Pivotal Trial of Axicabtagene Ciloleucel for the Treatment of Aggressive, Refractory Non-Hodgkin Lymphomas

Kathleen McDermott, RN, BSN, OCN, BMTCN1; Amy Patterson, RN2; Nicole Kahle, RN2; Alix Beaupierre, RN, BSN, OCN2; Maritza C. Alencar, DNP, ARNP-BC, BMTCN3
1Dana-Farber Cancer Institute, Boston, MA; 2Moffitt Cancer Center, Tampa, FL; 3Sylvester Comprehensive Cancer Center, Miami, FL 

Background: Chimeric antigen receptor (CAR) T cells are engineered from a patient’s own immune cells to redirect them to attack tumor cells. ZUMA-1 (NCT02348216) evaluated the anti-CD19 CAR T-cell therapy, [ Read More ]

Category IX: Clinical Research, Eighth Annual AONN+ Conference Abstracts

Treatment Options for Premenopausal Women with Hormone Receptor–Positive (HR+), Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Advanced Breast Cancer (ABC)

Jill Schwartz Gomez, RN; Mary Lynn Breslin, RN, BSN, OCN
MD Anderson Cancer Center, Houston, TX 

Background: Breast cancer occurs predominantly in older, postmenopausal women (>50 years), although the incidence of ABC in younger, premenopausal women is increasing.1 Younger patients often experience aggressive disease and are [ Read More ]