Breast Cancer

Breast Cancer

Abemaciclib (Verzenio™), a Novel CDK4/6 Inhibitor, in the Treatment of Hormone Receptor–Positive, HER2-Negative Advanced Breast Cancer

Introduction Based on current incidence rates, 12.4% of women born in the United States today will develop breast cancer at some time during their life.1 At the time of diagnosis, [ Read More ]

Breast Cancer, Web Exclusive

Breaking News: Sellas Announces Promising Data on NeuVax in Combination with Herceptin in HER2 1+/2+ Breast Cancer

This week Sellas Life Sciences Group announced data from a study of NeuVax (nelipepimut-S) in combination with Herceptin (trastuzumab) in patients with HER2 1+/2+ breast cancer. All node-negative (N0) patients [ Read More ]

Breast Cancer, San Antonio Breast Cancer Syposium

2017 San Antonio Breast Cancer Symposium: Program Highlights

The 40th anniversary of the San Antonio Breast Cancer Symposium was attended by approximately 8000 healthcare professionals and featured presentations ranging from basic science to preliminary clinical trials and new [ Read More ]

AONN+ Conference Highlights, Breast Cancer

The Complexities and Challenges of Navigation in Breast Cancer

Navigating patients through the complexities of breast cancer is a unique challenge, but cross-collaboration between breast patient navigators and oncology nurse navigators can make a world of difference in improving [ Read More ]

Breast Cancer, Original Research, Psychosocial Support Services/Assessment

Where Fear Begins: The Effect of a Nurse Navigator Home Visit to Decrease Distress in Newly Diagnosed Breast Cancer Patients

Ruth Smith, DNP, RN, CN-BN1; Sarah E. Mannle, DNP, FNP-C2; Kae R. Livsey, MPH, PhD, RN2; Elizabeth Tait, PhD2; John C. Rossitch, MD1
1Carolinas HealthCare System NorthEast, Concord, NC; 2Western Carolina University, Cullowhee, NC 

Background: Patients newly diagnosed with breast cancer face overwhelming distress and fear, often due to a deficit of knowledge about the disease and expectations regarding a cancer diagnosis. Research shows [ Read More ]

Breast Cancer

Breast Cancer Treatment

Sharon S. Gentry, RN, MSN, CBCN, CBEC, ONN-CG
Breast Nurse Navigator
Novant Health Derrick L. Davis Cancer Center
Winston-Salem, NC 

A treatment decision-making process by the patient begins once a breast cancer diagnosis is confirmed, and Byers states a navigator requires advanced clinical skills to support patients undergoing cancer treatment.1 [ Read More ]

Breast Cancer, Original Research

Cognitive Behavioral Therapy for Insomnia in a Patient with Breast Cancer

Laura Melton, PhD, ABPP
University of Colorado Anschutz Medical Campus, Aurora, CO 

Abstract: Cognitive and behavioral therapy techniques have been found to be helpful in treating insomnia and other sleep disorders. Higher rates of insomnia occur in the cancer population than the [ Read More ]

2017 American Psychosocial Oncology Society Annual Conference, Breast Cancer

Considering Genetic Testing? A Decision Support Tool for Young Women with Breast Cancer

A decision support tool for young breast cancer patients considering genetic testing for BRCA1/2 proved to be acceptable and feasible in a pilot study in the United Kingdom. Younger breast [ Read More ]

2017 American Society of Clinical Oncology Annual Meeting, Breast Cancer

Olaparib Is First PARP Inhibitor to Show Advantage in BRCA-Mutated Breast Cancer

The PARP inhibitor olaparib significantly improved progression-free survival (PFS) compared with standard chemotherapy in women with HER2-negative metastatic breast cancer with a germline BRCA mutation. Disease progression was delayed by [ Read More ]

Breast Cancer

Advancing High-Value Early-Stage Breast Cancer Care

Cancer costs are rising, but the implementation of evidence-based quality improvement strategies in early-stage breast cancer care can reduce costs and improve patient quality of life, according to Angie Meillier, [ Read More ]

Breast Cancer, The Round Table: Insight From Expert Navigators

The Controversies of How to Manage a Diagnosis of DCIS for Breast Cancer Patients

Lillie D. Shockney, RN, BS, MAS, ONN-CG,
The Johns Hopkins Breast Center; the Sidney Kimmel Cancer Center at Johns Hopkins,
Baltimore, MD

 

Approximately 55,000 cases of ductal carcinoma in situ (DCIS) are diagnosed each year in the United States. DCIS is known to be the earliest form of breast cancer that can [ Read More ]

Breast Cancer

Review of Ribociclib for Advanced Hormone Receptor–Positive Breast Cancer

Lowell L. Hart, MD 

Approximately 1 in 8 women in the United States will have invasive breast cancer during their lifetime, making breast cancer one of the most common cancer diagnoses in women.1 Breast [ Read More ]

Breast Cancer, Perspectives

Treatment of Advanced Breast Cancer: A Clinical Pharmacy Perspective

By Val R. Adams, PharmD, FCCP, BCOP, and Allison R. Butts, PharmD, BCOP
Dr Adams is Associate Professor, Pharmacy, Program Director, Hematology/Oncology Pharmacy Residency; Dr Butts is Hematology/Oncology Clinical Pharmacist and Adjunct Assistant Professor, Pharmacy, Comprehensive Breast Care Center, University of Kentucky HealthCare, Lexington

 

At the Markey Cancer Center in Lexington, KY, clinical pharmacists are integral members of the multidisciplinary care team, working in the clinic alongside surgical and medical oncologists, imaging specialists, radiation [ Read More ]

Breast Cancer, Perspectives

The Importance of Patient Education: A Nurse’s Perspective

Lillie D. Shockney, RN, BS, MAS, ONN-CG,
The Johns Hopkins Breast Center; the Sidney Kimmel Cancer Center at Johns Hopkins,
Baltimore, MD

 

It is exciting to see that patients with advanced breast cancer are able to receive additional treatment options, because a primary concern of patients with stage IV breast cancer is [ Read More ]

Breast Cancer, Perspectives

Increasing Focus on Value Related to Cancer Drugs: A Payer Perspective

Matthew P. Mitchell, PharmD, MBA, FAMCP
Director, Pharmacy Services, SelectHealth, Murray, UT

 

Breast cancer is a hot topic among payers. Approximately 12% of women will have invasive breast cancer in their lifetime.1 In 2017 alone, more than 250,000 new cases of invasive [ Read More ]

Breast Cancer, Original Research

Quantifying the Relational Dimensions of Study Staff in a Randomized Controlled Trial Among African American Women Recommended to Receive Breast Cancer Chemotherapy

Sarah F. Gallups, RN, BSN, MPH; Mary Connolly, RN, BSN; Jacqueline Simon, BA;
Margaret Q. Rosenzweig, PhD, FNP-C, AOCN, FAAN
University of Pittsburgh School of Nursing, Pittsburgh, PA

 

Background: The Adherence, Communication, Treatment, and Support (ACTS) randomized controlled intervention study was a one-time psychoeducational intervention encouraging adherence of African American women to prescribed chemotherapy. Surprisingly, 98% of both [ Read More ]

Breast Cancer, ESMO 2016

Potentially Practice-Changing: Ribociclib/Letrozole Combo in Advanced Breast Cancer

The addition of the selective CDK4/6 inhibitor ribociclib to letrozole significantly improved progression-free survival (PFS) in hormone receptor–positive (HR+) advanced breast cancer. Compared with letrozole alone, the combination of ribociclib/letrozole [ Read More ]

Breast Cancer, Letters from Lillie

JONS Celebrates Breast Cancer Awareness Month

Lillie D. Shockney, RN, BS, MAS, ONN-CG 

Dear Navigators, Over the past couple of decades, our country has made impressive progress in raising awareness of breast cancer. From races for the cure to pink gear on NFL [ Read More ]

Breast Cancer, Interview with the Innovators

Early Recurrence Detection: Analyzing DNA from Circulating Tumor Cells and Circulating Cell-Free DNA

An Interview with Paul W. Dempsey, PhD, and Paul Y. Song, MD, of Cynvenio

Cynvenio is a cancer diagnostics company offering their Liquid­Biopsy technology to provide molecular analysis of cancer biomarkers in blood. The company purports that molecular diagnostic approaches to cancer detection and [ Read More ]

Breast Cancer

Endocrine Therapy Options for Women with Breast Cancer

Endocrine therapy is a valuable treatment option for women whose breast tumors express the estrogen receptor (ER).1 In these women, endocrine therapy can block the tumor’s ability to produce estrogen–a [ Read More ]

Breast Cancer, Survivorship

The Transformation of Breast Cancer Management

Sharon S. Gentry, RN, MSN, CBCN, CBEC, ONN-CG
Breast Nurse Navigator
Novant Health Derrick L. Davis Cancer Center
Winston-Salem, NC 

If you are a female in the United States, your lifetime risk of being diagnosed with breast cancer is 1 in 8.1 If you are a male, the risk is [ Read More ]

Breast Cancer

Studies Show the Breast Cancer Index Can Help Guide Treatment Strategy for Patients with Early-Stage Invasive Breast Cancer

The Breast Cancer Index (BCI) test is a quantitative assay based on the expression of 11 genes that may help patients with estrogen receptor–positive (ER+), early-stage breast cancers, in consultation [ Read More ]

Breast Cancer, Original Research

State of Personalized Medicine in Breast Cancer

Sarika Jain,1 Sachin G. Pai,2 Cesar A. Santa-Maria,1 William J. Gradishar1
1Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 2Northwestern Medicine Developmental Therapeutics Institute, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 

It was estimated that 231,840 new breast cancers would be diagnosed in 2015, with 40,290 breast cancer–related deaths during the same period in the United States alone.1 With improvements in [ Read More ]

AONN+ Conference Abstracts, Breast Cancer, Patient Education and Assistance

Developing the First Global Breast Cancer Education Campaign: Findings on Patient Knowledge and Effective Communication Design

Corrine Ellsworth Beaumont, PhD
WorldwideBreastCancer.com 

Background: Each year, breast cancer kills more than 500,000 women worldwide (World Health Organization [WHO], 2016). In resource-poor settings, most are diagnosed at an advanced stage, with survival rates ranging [ Read More ]

AONN+ Conference Abstracts, Breast Cancer, Patient Education and Assistance

Identifying Gaps in Metastatic Breast Cancer Patient Knowledge and Their Communication Experiences with Healthcare Professionals

Corrine Ellsworth Beaumont, PhD1; Katherine Crawford-Gray, MBA, MSc2
1WorldwideBreastCancer.com; 2Metastatic Breast Cancer Alliance 

Objectives: When patients are told they have metastatic breast cancer (MBC), it’s very difficult for them to absorb and interpret what is being told to them at the time of [ Read More ]

AONN+ Conference Abstracts, Breast Cancer, Patient Education and Assistance

Using the Power of Design to More Effectively Communicate with Metastatic Breast Cancer Patients, the “Dandelion Toolkit”

Corrine Ellsworth Beaumont, PhD1; Katherine Crawford-Gray, MBA, MSc2
1WorldwideBreastCancer.com; 2Metastatic Breast Cancer Alliance 

Background: Metastatic breast cancer (MBC) patients receive an overwhelming amount of information at the time of diagnosis, with most of the information transferred through oral conversations and abstract medical terminology [ Read More ]

AONN+ Conference Abstracts, Breast Cancer, Research/Quality/Performance Improvement

Navigator Identification of Breast Biopsy Results: A Time Analysis of Biopsy Results and Variance in Turnaround Time

Laurie A. Dressman, RN, BA
Sarah Cannon Cancer Institute, Kansas City 

Objective: To improve the turnaround time of breast cancer biopsy pathology to maximize patient care. This includes: Interval between date biopsy performed and initial result showing type of breast cancer [ Read More ]

Breast Cancer, Research/Quality/Performance Improvement

Overcoming Barriers to Lymphedema Education and Treatment for Breast Cancer Patients in Rural Eastern North Carolina

Debra C. Mascarenhas, RN, BSN, BSBA, CBCN; Allyson H. Daugherty, PT, CLT, CFM; Judy Koutlas, RN, MS, OCN
Vidant Medical Center: 

Background: Approximately 42% of breast cancer survivors develop clinically detectable lymphedema within 5 years of treatment. Lymphedema risk factors include axillary node surgery, radiation therapy, infection, tumor growth, and obesity. [ Read More ]

Breast Cancer, Original Research

The Breast Imaging Nurse Navigator: Measuring the Impact on Coordinated Care Delivery – Results After the First Year

Sharon Inzetta, RN, MS, CBCN, CN-BN
Summa Health System Akron City Hospital Breast Center, Akron, OH 

Objectives: Access, timeliness, patient satisfaction, and outmigration for breast care delivery were all identified as areas for process improvements in our community hospital breast center. In 2015, a dedicated imaging [ Read More ]

Breast Cancer

AltaMed Health Services: Breast Cancer Outreach and Screening Program

Marlene Luna, MPH; Arlene Bruins, MS
AltaMed Health Services 

Objective: Women living in Los Angeles and Orange County have low mammography screening history; only 65.6% of women have had a mammogram in the past 2 years or less.1 Research [ Read More ]

Breast Cancer

Implementing a Breast Screening Assessment Tool in the Inpatient Setting

Nicole DeLano, MSN, RN; Steven Lane, MD; Melissa DeMayo, MSN, RN, LNC
Signature Healthcare 

Problem Addressed: In a recent discussion review on the number of women being screened at the Women’s Imaging Center, the nurse navigator noticed that there was no screening program for [ Read More ]

Breast Cancer

Pathway of a Positive Breast Biopsy: Reducing Testing to Treatment Times

Linda Byrd, ADN, RN-BC, CGRN
Emory Saint Joseph’s Hospital, Atlanta, GA 

Objective: In a suburban community hospital where turnaround times for hormone receptor reports of positive breast biopsies averaged 8 business days, resulting in delayed initiation of treatment, an interdisciplinary breast [ Read More ]

Breast Cancer, Clinical Research

45. Eight Case Studies of Concurrent Pathogenic Mutations Identified in Hereditary Breast and Ovarian Cancer Gene Panel

Lilian Servais, MS, LCGC; Lauren Ryan, MS, LCGC; Jeroen Van den Akker, PhD; Annette Leon, PhD, MS, FACMG
Color Genomics 

Objectives: The availability of next-generation sequencing (NGS) and characterization of multiple genes that can increase cancer risk have caused a shift toward multigene panel testing for hereditary cancer. However, the [ Read More ]

Breast Cancer, Original Research

A Pilot Study of a Virtual Navigation Program to Improve Treatment Adherence Among Low-Income Breast Cancer Patients

Kathy J. Helzlsouer1,2; Susan E. Appling1,3; Lisa Gallicchio1,2,4; Dawn Henninger5; Ryan MacDonald1; Shannon Manocheh1; Susan Scarvalone1; Arti P. Varanasi6
1The Prevention and Research Center, Mercy Medical Center, Baltimore, MD
2Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD
3Johns Hopkins University School of Nursing, Baltimore, MD
4Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD
5Center for Cancer Prevention and Control, Maryland Department of Health and Mental Hygiene, Baltimore, MD
6Advancing Synergy, LLC, Baltimore, MD
 

Background: Socioeconomic disparities negatively impact completion of adjuvant breast cancer treatment. Navigation programs may improve treatment completion but may not be accessible to all patients, especially in low-resource communities. Objectives: [ Read More ]

Breast Cancer, Original Research

Development and Evaluation of a Technology-Enhanced Interdisciplinary Navigation Program for Low-Income Breast Cancer Patients

Kathy J. Helzlsouer; Susan E. Appling; Susan Scarvalone; Shannon Manocheh; Ryan MacDonald; Lisa Gallicchio; Dawn Henninger; Arti P. Varanasi 

Background: Navigators have the potential to help overcome barriers that interfere with cancer treatment adherence, but their widespread use is economically challenging, especially in rural and low-resource communities. A centrally [ Read More ]

Breast Cancer, Original Research

A Feasibility Study of a Virtual Navigation Program for Low-Income Breast Cancer Patients

Kathy J. Helzlsouer; Susan E. Appling; Susan Scarvalone; Shannon Manocheh; Ryan MacDonald; Lisa Gallicchio; Dawn Henninger; Arti P. Varanasi 

Background: Socioeconomic disparities negatively impact completion of adjuvant breast cancer treatment. Navigation programs may improve treatment completion but may not be accessible to all patients, especially in low-resource communities. Objective: [ Read More ]

Breast Cancer, Patient Navigation

Patient Navigation Success Varies Among Different Groups of Women with Breast and Gynecologic Cancers

Christine Erickson 

Patient navigation is a patient-centered healthcare delivery method that assists patients in overcoming barriers to oncology care throughout the cancer care continuum. Patient navigation is especially helpful for patients with [ Read More ]

Breast Cancer, Survivorship

Patients’ Views of Follow-Up Care After Treatment for Breast Cancer: A Comparison of 2 Approaches

Samantha Muktar, MBBS, MRCS, BMedSci; Paul T. R. Thiruchelvam, BSC, MBBS, FRCS, PhD; Dimitri Hadjiminas, MPHi, FRCS 

Background: Improved diagnostic methods and treatments for breast cancer have resulted in more survivors requiring follow-up care. Objectives: To assess patients’ views on breast cancer follow-up care and examine the [ Read More ]

Breast Cancer, Survivorship

Treating Sexual Dysfunction in Breast Cancer Survivors

Chase Doyle 

San Francisco, CA—Sexual dysfunction is prevalent in women with breast cancer, and is a consequence of treatment that pre- and postmenopausal women receive. As reported at the 2015 Breast Cancer [ Read More ]

Breast Cancer, Survivorship

Addressing Fertility Issues in Patients with Breast Cancer

Chase Doyle 

Fertility and early menopause after cancer can pose challenging emotional and medical issues for patients and their clinicians. Survivors who become infertile because of their cancer treatment are at an [ Read More ]

Breast Cancer, Survivorship

Knowledge of Previous Treatments and Appreciation of Future Health Concerns Among Breast Cancer Survivors

Grace Makari-Judson, MD; Chandravathi Loke, MD; Deborah Katz, MD; Wilson C. Mertens, MD, MSBA 

Background: Breast cancer survivors’ understanding of treatment and future health risks is needed to gain insight into unmet survivorship needs in this population. Objectives: To assess breast cancer survivors’ recall [ Read More ]

Breast Cancer, Survivorship

Transitioning Patients After Breast Cancer Treatment: Implementing Survivorship Care Plans

Susan Hope Klein, DNP, FNP-C, OCN; Shelley Y. Hawkins, PhD, FNP-BC, GNP, FAANP 

Background: The success of cancer treatments has resulted in rapid growth in the number of survivors, providing the impetus for the oncology community to examine models of care supporting smooth [ Read More ]

Breast Cancer, Interview with the Innovators

Providing Therapeutic Guidance for Breast Cancer Patients in the Molecular Era With the Breast Cancer IndexSM Assay:

An Interview with Stephen C. Malamud, MD, and Susan K. Boolbol, MD, of Mount Sinai Beth Israel Hospital

With the advent of gene expression profiling, we have gained the ability to objectively advise patients with breast cancer, among other cancers, on their risk of recurrence and potential benefit [ Read More ]

Breast Cancer, The Patient's Voice

I Get By with a Little Help from My Friends: The Role of the Support Group in Breast Cancer Survivorship

Carolyn Cormeau 

Wow, those meetings must be sober events.” I’ve gotten this and other similar comments regularly over the past 6½ years since I received my diagnosis of stage III breast cancer [ Read More ]

AONN+ Conference Highlights, Breast Cancer, Survivorship

Breast Cancer Navigation and Survivorship

Lisa A. Raedler, PhD, RPh 

Memphis, TN—One of the most popular breakout sessions at the Fourth Annual Conference of the Academy of Oncology Nurse & Patient Navigators (AONN+) focused on breast cancer navigation and survivorship. [ Read More ]

AONN+ Conference Abstracts, Breast Cancer, Coordination of Care/Care Transitions

Category III: Tracking Processes Across the Continuum of Care

Monitoring High-Risk Breast Cancer Patients in a Community Breast Health Center Through Implementation of a Plan of Care Tool Sara Hartke, RN, BSN, OCN Centegra Gaver’s Breast Center Background: Initiation [ Read More ]

Breast Cancer, Original Research

Navigation Needs for Breast Health and Breast Cancer Populations in Low- and Middle-Income Countries

Lillie D. Shockney, RN, BS, MAS, ONN-CG 

Breast cancer remains the most feared disease by all women, unrelated to their race, ethnicity, or age. Among major cancers, cancer of the breast is the most common cancer in [ Read More ]

AONN+ Conference Abstracts, Breast Cancer, Community Outreach and Prevention

Innovative Research-Based Educational Tools/Resources to Improve the Breast Cancer Screening Experience for Women With Disabilities

Linda Muraca, RN, MN 

Background: Women with disabilities (WWD) have the same biological risk of developing breast cancer as nondisabled women but are less likely to participate in regular cancer screening. A previous community-based [ Read More ]

AONN+ Conference Abstracts, Breast Cancer

Patient Navigation: Blending Imaging and Oncology in Breast Cancer

Jeanne Chaivous, MSW 

Background: Patient navigation (PN) in cancer care refers to the individualized care provided to the breast cancer patients, families, and caregivers to ease multiple barriers and facilitate timely access to [ Read More ]

AONN+ Conference Abstracts, Breast Cancer

Breast Nurse Navigator Role Impacts Timeliness of Care for Breast Cancer Patients

Loril Garrett, BSN, RN, OCN, CBPN-IC, CBCN 

Background: Breast cancer care is delivered by multiple providers over an extended period of time within an already fragmented healthcare system, which has led to gaps in the care process. [ Read More ]

AONN+ Conference Abstracts, Breast Cancer

Strength & Courage: Exercises for Breast Cancer Survivors DVD

Sharon Cowden, MD 

Objectives: Medical research indicates that exercise for breast cancer survivors is safe and beneficial not only during recovery but also after treatment is completed. Aerobic exercise may even prevent the [ Read More ]

Breast Cancer

Beyond the Shock: An Online Resource From the National Breast Cancer Foundation

Lillie D. Shockney, RN, BS, MAS, ONN-CG 

The mission of the National Breast Cancer Foundation is to save lives through early detection and to provide mammograms for those in need. The goals of the foundation include increasing [ Read More ]

Breast Cancer, Original Research

Stress Therapy Empowering Prevention (STEP): A Healthy Lifestyle Program for Breast Cancer Patients

Amy M. Burke, RN, BSN 

Purpose: Develop and implement a comprehensive program for lifestyle change, empowering breast cancer patients to manage stress effectively and improve their mental and physical health. Method: Women with breast disease [ Read More ]

AONN+ Conference Highlights, Breast Cancer

Breast Cancer Navigation: 5 Steps to Better Navigation

Sue Bowman, RN, OCN, CBCN, MSW 

The breast cancer session focused on the use of the Nursing Process to guide navigation for people with breast cancer. A review of the Nursing Process theory was aligned to [ Read More ]